Dosing and Administration of drugs: injected V / m or p / w 1 per month, the injection time to modify; prostate cancer: single dose is 3.75 mg or 7.5 mg endometriosis and uterine fibroids - 3 75 mg (for women of reproductive age first injection administered on Day 3 of menstruation), duration of treatment - no more than 6 months; Mr injection prepared immediately before administration, using the solvent in the concentration of 3.75 mg / 1 ml angora . Antineoplastic and immunomodulating agents. Dosing and Administration of drugs: breast cancer: 500 mg daily; endometrial cancer: 200-500 mg daily, therapy should be continued until no observed effect of treatment (sometimes after 10.6 weeks of treatment) in times of patient deterioration - treatment should be discontinued. Side effects and complications in the use of drugs: early treatment - Transient increase levels of serum testosterone, which can lead to a temporary activation of the tumor with secondary reactions - the emergence or strengthening of bone pain in patients with metastases in bones, neurological disorders due to tumor compression of nerves ( weakness in the lower extremities; breach outflow of urine, hydronephrosis or lymphostasis; thrombosis with pulmonary embolism) this can be prevented if the accompanying prescribing treatment of prostate cancer at an early phase of treatment buserelinom, however, even with concomitant therapy treatment of prostate cancer in some patients may develop a small Transverse Rectus Abdominis Myocutaneous Flap transient increase of pain in the area of the tumor, as well as deterioration of general condition, you may receive an additional hot flushes and loss of potency or libido - painless gynecomastia, slight swelling of the shins and feet; angora of pituitary adenomas, increasing or reducing hair on the body, loss of control angora levels in patients with hypertension, hypersensitivity reactions (redness, itching, skin rashes, including nettles `yanku), asthma, anaphylactic / anaphylactoid shock, decrease glucose tolerance (with accompanying diabetes possible loss of metabolic control), changes in blood lipids, increased levels of serum bilirubin or liver enzymes, leukopenia and thrombocytopenia, headache (in rare cases mihrenepodibnoho), strengthened heart beat, nervousness, sleep angora fatigue, sleepiness, disorders of memory and concentration, emotional instability, anxiety, depression, dizziness, tinnitus, sleep disturbance, blurred vision, Henderson-Hasselbach Equation "pressure" for the eyes, nausea, vomiting, increased thirst, diarrhea, constipation, change in appetite, change in body weight, musculo-skeletal discomfort and pain, possible association with reduced density bones and can lead to osteoporosis and increased risk of bone fracture; ∙ pain or local reactions at the injection site. № 1. The main effect of pharmaco-therapeutic effects of drugs: antitumor effects, the use of appropriate doses hozerelinu provides effective action without clinically significant accumulation. Contraindications to the use of drugs: hypersensitivity to the drug. for p / w input prolonged by 3.6 mg or 10.8 mg in a syringe-applicator with a protective mechanism number 1. Dosing and Administration of drugs: adult men: one cap.
2012年4月11日 星期三
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