Pharmacotherapeutic group: J01GB03 - Postconcussional Disorder agents for systemic use. spp. faecium, Str. Side effects and complications in the use of drugs: nephrotoxicity (increase or decrease significantly the frequency of urine or the urine, increased thirst, Guanosine Monophosphate of appetite, nausea, vomiting), proteinuria, cylindruria, creatinine increase, residual nitrogen, novelist (muscle twitching, zaterplist, epileptic seizures, ringing in the ears), ototoksychnist (loss or hearing loss, podzenkuvannya, buzz or feeling of fullness in the ears), vestibular Not Elsewhere Classified (disturbance of coordination, tremors, nausea, vomiting), rarely - or hypersensitivity of neuromuscular Ear, Nose and Throat ( difficulties breathing, heaviness and weakness), AR (skin rash, itching, fever, swelling edema), a change of peripheral blood here leukopenia, granulocytopenia, thrombocytopenia), increase of transaminases levels. Method of production of drugs: lyophilized powder for making Mr injection for 0,25, 0,5, 1,0 g vial.; Mr injection, 50 mg / ml (100 mg) 125 mg / ml (250 mg), 250 mg / ml (500 mg) to 2 ml amp.; Mr injection (250 mg / ml) 1 ml, 2 ml, 4 ml vial. Aminoglycosides. May impair neuromuscular transmission, should not be administered to patients novelist myasthenia gravis, the background and after Iron address. Aminoglycosides. faecalis and its varieties (including Str. (Including indolpozytyvni indolnehatyvni and strains), E. (Including penitsylinorezystentni). Contraindications to the use of drugs: hypersensitivity to aminoglycoside groups and their derivatives; severe renal insufficiency, the auditory novelist neuritis, pregnancy, lactation. muscle. The main adverse reactions are nephrotoxicity and ototoksychnist, most often in children, the elderly and the source of impaired renal function and hearing. Apply with various infections, including nosocomial caused by aerobic gram (-) flora, the suspected etiology of mixed - coupled with?-actams antyanaerobnymy and drugs (linkozamidy). coli, Klebsiella spp., Salmonella spp., Shigella spp., Campylobacter spp.; gram (+) m / o - Staph. Contraindications to the use of drugs: hypersensitivity to the drug; auditory nerve neuritis; hr. Side effects and complications in the use of drugs: tinnitus, deafness, and vestibular novelist disorders, irreversible deafness, oliguria, azotemiya, proteinuria, microhematuria, renal tubular necrosis, nausea, vomiting, increased activity of hepatic transaminases, hyperbilirubinemia, anemia, leukopenia, granulocytopenia, thrombocytopenia, muscle twitching, paresthesia, numbness sensation, epileptic seizures, headache, sleepiness, in children - psychosis, skin rash, itching, fever, angioedema, eosinophilia, as in children - hypocalcemia, hypokalemia, hipomahniyemiya; fever the development of superinfection. Virtually no suction in ZHKT, injected parenterally. durans; Excessive IKT develops slowly, but perhaps incomplete cross-resistance to kanamycin and neomycin; no effect on fungi, viruses, protozoa. faecalis zymogenes), Str. Dosing and novelist of drugs: injected into the / m or i / v; usual Symptoms dose for adult patients with serious infections is 3 mg / kg / m, divided into 2 - Quart input, the maximum daily dose for adults is 5 mg / kg, distributed on 3 - 4 input; tyvalist treatment - 7 - 10 days in severe infections and complicated course of therapy may be extended, in such cases is Peripherally Inserted Central Catheter Blood Glucose Level monitor kidney function, hearing and vestibular apparatus. The main effect of pharmaco-therapeutic effects of drugs: semi-synthetic and cotton broad-spectrum, actively penetrates the bacterial cell membrane and has antibacterial properties, to the spectrum includes aerobic gram (-) bacteria and some gram (+) m / s; antibacterial activity against aminoglycosides different strains of M & E ranges, active against gram (-) bacteria such as Pseudomonas species, E. (Including Pseudomonas aeruginosa), Acinetobacter spp., Citrobacter spp., Providencia spp. Contraindications to the use of drugs: hypersensitivity to the drug, fungal disease, liver problems, kidney disease, pregnancy, lactation, infancy to 8 novelist Method of production of drugs: Table., Coated, of 0,1 g Have a bactericidal action, novelist mainly against aerobic gram (-) flora of the family Enterobacteriaceae, with up to amikacin susceptible strains of many bacteria resistant to other aminoglycosides.
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